Sentence examples for reporter response from inspiring English sources

Quantification of absolute cell numbers was not used because the number of cells expressing the reporter can differ between individual animals due to the variability of reporter response potentially caused by an epigenetic mechanisms as previously reported (Sakai and Dräger, 2010).

Mutation of predicted site 1, but not site 2, eliminated this reporter response.

We also confirmed that the gene copy number of the Sox2 reporter integrated into these 2 cell subsets was not significantly different (data not shown), and thus, the difference in their reporter response was genuine.

Recent findings, however, showed that clonal bacterial populations are essentially always physiologically, phenotypically and genotypically heterogeneous, thus emphasizing the need for sound statistical approaches for the interpretation of reporter response in individual bacterial cells.

Each of these knock-down conditions potentiated the β-catenin reporter response to co-transfected Wnt1 (Fig. 3D).

PPARγ fish treated with the receptor specific agonists Rosiglitazone (RGZ), Pioglitazone (PGZ) or Troglitazone (TGZ)) increased the GFP reporter response from the relatively restricted signal in tail epidermis and posterior spine to include strong expression in the CNS, heart, blood, renal tube and eye (Figure 4a).

Surprisingly, however, both of these SBE sites also proved non-functional; as for the SBE site at -1.41 kb mutation of the SBE sites at positions -2.66 and -3.67 kb did not alter reporter responses in transient transfections of SW480 cells (constructs d, e) and other TGFβ responsive cell lines (Smad4-reconstituted BxPC3, LT97, Hacat; data not shown).

The suppression of reporter responses by ER stress should be considered carefully for experimental design and interpretation of data when secreted protein-based reporter systems are used for investigation.

The induction of miR-17* by DSF is further confirmed by reporter responses that are regulated by miR-17* targeting sequences (Fig. 2D).

As shown in Fig. 1D, the cloned miR-17* targeting sequences are necessary for the repression of reporter responses by transfected miR-17*.

Moreover, mutation of the putative SBE site at -1.41 kb (construct b) did not alter reporter responses neither in SW480 cells (Fig. 4) nor in BxPC3 cells (data not shown) suggesting that this site is not functional.