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Since Pin1 was reported to stabilize p73 proteins, we asked if Pin1 is involved in regulating p63 protein stability.
Screw fixation of the facet joint has been reported to stabilize the lumbar spine and facilitate spinal fusion.
Oleic acid is reported to stabilize TiO2 nanoparticles in DI water [20] and was added to the mixture at 0.01vol.% concentration.
However, only SENP6 and no other SUMO2/3 specific SENPs has been reported to stabilize their substrates (Mukhopadhyay et al., 2010).
However, among the SUMO2/3 specific proteases, only SENP6 is reported to stabilize its substrate by antagonizing RNF4 (Mukhopadhyay et al., 2010).
The addition of rare earth elements, such as La, Gd, Dy, or Er, is reported to stabilize these phases and k-values of up to 40 have been obtained [7 11, 14].
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Enzyme immobilization and supplements of stabilizers (such as salts, sugars, surfactants) have been reported to effectively stabilize enzymes in presence of organic solvents (Stepankova et al. 2013).
Based on this fixed-cell assay with static end points, VHL has been reported to directly stabilize the MT cytoskeleton.
IgE binding to FcεRI was previously reported to both stabilize the receptors on the surface leading to receptor accumulation [32], but also to enhance survival of FcεRI bearing mast cells by autocrine cytokine secretion and induction of an anti-apoptotic protein [33].
On the other hand, oncogenic Ras has been reported to differentially stabilize TAp73α [ 29], an isoform that can interact with ∆Np73α and may be blocking its capacity to transactivate BIK.
More recently, pharicin B, a novel natural ent-kaurene diterpenoid derived from Isodon pharicus leaves, was reported to rapidly stabilize RARα protein in various AML cell lines and primary leukemic cells from AML patients [ 15].
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com