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In Drosophila, PcG complexes have been reported to regulate the expression of several cell-cycle regulators.
For example, zebrafish miR-214 was reported to regulate the slow muscle phenotype by targeting suppressor of fused (Sufu), a negative regulator of hedgehog signaling [ 23].
We next examined GSK3, another kinase that has been reported to regulate the migration and morphology of cortical neurons37, possibly via semaphorin signaling pathways4,38,39.
Goreisan has also been reported to regulate the function of the intestines and show an antiemetic effect [14 16].
NEDDylation is reported to regulate the decision between the non-homologous end joining (NHEJ) pathway and different homologous recombination (HR) subpathways by controlling CtBP interacting protein (CtIP -mediated DNA reseCtIP -mediatedet al., 2015).
Tetraspanins have also been reported to regulate the activity and function of their associated molecules.
SP1 has been reported to regulate the basal EGFR promoter activity [35].
nNOS has been reported to regulate the structure and function of the neuromuscular synapse [15].
PAK1 has been reported to regulate the ERK pathway by direct interaction between PAK1 and Raf and MEK.
MiR-126 [42], [42] and miR-23a [43] have been previously reported to regulate the expression of CXCL12.
Since then, EHD1 has been reported to regulate the recycling of a wide array of receptors, including CFTR [31].
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