Although AtMYB3 and AtMYB7 have not been functionally characterized, AtMYB4 has been reported to function as a repressor of the lignin biosynthesis pathway [ 25].
Oral supplementation of clay has been reported to function as buffer in dairy cows.
OsWRKY71 has also recently been reported to function as a transcriptional repressor (Chujo et al. 2008).
Notably, phenylalanine was previously reported to function as an inhibitor to lock PKM2 in an inactive T-state conformation (Morgan et al., 2013).
Squid ink was reported to function as antioxidant in hyperlipidemia rats and broil chicken (Lei et al. 2007; Liu et al. 2011).
Since these lectins have been reported to function as non-self recognizing molecules, we believe that Dorin M may play a similar role in an innate immunity of the tick and, possibly, also in pathogen transmission by this vector.
Recently, PKM2 has been reported to function as a nuclear protein kinase to regulate gene transcription and promote tumorigenesis (Gao et al., 2012; Yang et al., 2012a, b; Gao et al., 2013; Lv et al., 2013; Keller et al., 2014).
Rab32 has been reported to function as an A-kinase anchoring protein in mitochondria [46] and melanosomes [47].
On the other hand, Rab32 has been reported to function as an A-kinase anchoring protein in mitochondria [46] and melanosomes [47] of mammals.
Non-coding transcripts have been reported to function as gene regulators [40]; thus, the information on non-coding transcripts is also important to reveal transcription regulation.
Strikingly, TEs are associated with many evolutionarily constrained regions in mammalian genomes [46], and many conserved non-coding elements are reported to function as transcriptional enhancers [47].
