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Sphingomyelin levels were also reported to be elevated in prodromal stages of Alzheimer's compared to control [91].
Myelin basic protein (MBP) levels in the cerebrospinal fluid (CSF) have been reported to be elevated in DNS.
DUPAN-2 was reported to be elevated in pancreatic cancer, biliary tract cancer, and some benign diseases, especially obstructive jaundice [18, 19].
Also, C5a and C5a receptor expression levels were reported to be elevated in the lung, liver, kidney, pituitary gland, and heart during sepsis [5, 15].
Expression of Cav-1 was reported to be elevated in cells exposed to IR [33], [34].
Recently, a few inflammatory mediators have been reported to be elevated in the tear fluid of keratoconus patients.
The cysteine proteinase inhibitor cystatin C was also reported to be elevated in CSF of sCJD patients [15], [16].
MCP-1 levels was also reported to be elevated in diabetic patients with coronary artery disease [29], [30].
Circulating concentrations of heme oxygenase-1 (HO-1) have been recently reported to be elevated in several chronic disorders.
Along with IgE, IgG4 has been reported to be elevated in several helminthiasis [23] as well as allergic disorders [24].
In vivo, synoviolin has been reported to be elevated in a subset of circulating immune cell subsets which may be associated with anti-TNF nonresponse [3].
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