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When following previously reported procedures for the production of 3 and 4 in SB12029, we discovered that 1 and 2 were also produced in high titers8.
This is the first report of the use of ketones in contrast to aldehydes in all the earlier reported procedures.
Notably, the new route avoids the intractable workups and byproducts previously reported procedures have been associated with, thereby making this approach highly attractive to adaptation with other heterocyclics.
We developed a method for genotyping Y chromosome-linked homologous DYS385 loci individually, combining locus-specific polymerase chain reaction (PCR) amplification and previously reported procedures.
[11C]HMS011 was prepared by previously reported procedures [11].
Some of the reported procedures endure drawbacks such as long reaction times, and undesirable reaction conditions.
The intermediate chloromethylquinazolinones (1 10) were prepared following reported procedures from anthranilic acid in two steps [36 39].
The experiments were conducted at least three times for each catalyst to confirm the reproducibility of the reported procedures.
The efficiency of the separation methods is consistent with the previously reported procedures for separation of 44Sc from enriched and natural targets [9, 10, 13].
The total bonded hydrogen concentration (CH) was estimated from the integrated absorption of the 640 cm−1 rocking mode using previous reported procedures [26, 27].
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DNA isolation was carried out on young true leaves, according to previously reported procedures [ 49].
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