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We have two variations of the single seed method: ' k-mer/nonredundant' stores previously reported pairs in memory, and does not include previously reported pairs in candidates.
If a study reported pairs of sensitivities and specificities at different cut-off points, we extracted the pair with the highest sensitivity.
The results presented here are for using a cutoff for the correlation coefficient of 0.4, but qualitatively they are similar for higher cutoffs (only the number of reported pairs is lower).
Five participating centers reported pairs of results that were very close to each other (average intra-center CV < 30) for most of the eight depicted antigen-donor combinations showing that reproducibility within an acceptable range can be obtained for a broad range of detected antigen-specific T cell responses.
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Heng et al.21 reported paired maternal whole blood gene expression changes from 17 23 weeks to 27 33 weeks of gestation in 114 women with term delivery.
SVDetect offers different output formats to facilitate the subsequent analysis of reported paired-end clusters.
Ten studies reporting paired air and urine mercury data (149 samples total) met criteria for data quality and sufficiency.
Future test accuracy studies must report paired results for detection of HPV in urine and cytology or biopsy outcomes so that this can be meta-analysed.
Reported SNP pairs are validated against the linear model.
The reported biomarker pairs also appear useful for detecting age-related brain changes.
Reported FRET pairs containing red fluorescent acceptors suffer from tetramerization and demonstrate lower contrast [ 16, 17].
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