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The rate of adverse effects reported over the study period is presented in Table 2.
Overall, 9.1 cases of listeriosis/million FCEs were reported over the study period (95% CI 8.6 9.6) (Table A1).
The most frequent PPI was Senegal where 37 cases were reported over the study period (5 family-related outbreaks) and India (n = 21 cases) where cases were reported in all but 3 years of the study period.
For example, the pooled mean rate of vancomycin use was calculated for each ICU by dividing the total number of defined daily doses by the total number of patient-days reported over the study period by that ICU, multiplied by 1,000, and thus expressed as defined daily doses per 1,000 patient-days.
When the proportion of capacity assessments was broken down by month there was a significant decrease in the frequency of incapacity reported over the study period (regression coefficient −0.427, 95% CI −0.623 to −0.230, p = 0.0001) showing a reduction of 0.4 percentage points per month.
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Table 7 shows types and frequencies of adverse events (AE) in ITT population reported over the whole study period including 6 month follow-up.
Three deaths were reported over the 7-year study period.
In one study of patients' attitudes towards healthcare professionals collecting data on ethnicity and race, Baker reported over half the study population to be either somewhat or very concerned (51.2%) that the data would be used to discriminate against them [ 19].
A total of 243 AEs were reported over the course of the study with 54.7% in the AET group and 45.3% in the SMT group.
Although an increase in articles by medical students has been reported over the years, these studies are rarely cited [ 2].
The concordance between data reported over the first year of the study [ 10] and the global results appear to reinforce the reliability of our analysis.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com