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Co-morbidity was categorised as either none or one or more reported morbid conditions.
In the epilogue to The Dead Hand, written two years ago, Hoffman describes bin Laden's reported morbid interest in the 1995 Tokyo subway attack with the deadly nerve agent sarin.
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Morbid procedures were more commonly reported than morbid diagnoses; 5359 (85.8%) women underwent one or more procedures, and 1255 (20.1%) women had at least one diagnosis indicating an adverse outcome.
Pre-existing conditions reported were: morbid obesity/obesity (n=5, 24%), lung disease (n=4, 19%), heart disease (n=3, 14%), pregnancy (n=3, 14%), diabetes (n=1), immunodeficiency (n=1), cerebral palsy (n=1), prematurity in an infant (n=1) and genetic disorder (mitochondrial disease) (n=1).
The most frequently reported co-morbids were diabetes (23.1%) and ischemic heart disease (25.8%).
Depression and anxiety disorders are commonly reported co-morbid conditions in CWP [ 26, 29, 47, 54- 57].
A number of patients reported co-morbid conditions within the 3 months prior to their participation in the study.
The most commonly reported co-morbid conditions impacting on patient ability to manage CHF were depression (n = 9), diabetes (n = 5), arthritis (n = 3) and asthma (n = 2).
The mean Charlson co-morbidity index score was 5 (sd = 3) points and the most frequently reported co-morbid conditions included 46%% (n = 96) having moderate to severe renal failure and 34%% (n = 72) suffering with dementia.
Nonetheless, we constructed this co-morbidity score (that is based on 17 co-morbid conditions including various chronic pulmonary and other diseases) using a similar approach as demonstrated by Chaudhry et al. [ 30] who found high agreement levels between reported co-morbid conditions and those recorded in administrative datasets.
Exclusion of study participants reporting a morbid condition at baseline, and sensitivity analyses excluding the first 3 years of follow-up limited the chance that reverse causality affected the findings.
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