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These viruses clustered within a previously reported lineage named Central Plata.
A previously reported lineage limited to the Iberian Peninsula was confirmed.
Four strains (2.4 %) could not be classified to any earlier reported lineage thus were designated "ambiguous".
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The other dominant form represented by AAV2 is found in two previously reported lineages of human AAV, AAV2-like clade B represented by AAV2 and clade C represented by AAV2/3 hybrid isolates [10], [11].
Takahashi and Saitou (2012) previously reported lineage-specific highly conserved noncoding sequences (HCNSs), which were associated with some protein-coding genes.
The presence of various Rex1 lineages has been observed previously in fish genomes with four reported lineages for this retroelement [ 18].
Several trends are emerging: first, increasing labelling density with multiplexed markers to allow more cells to be reliably distinguished; second, using labels to report lineage relationships among defined cells in addition to anatomy; third, coupling cell labelling with genetic manipulations that reveal or perturb cell function.
More recently, it was reported that lineage and isolation origin correlate with Stx2 production [ 21].
However, these analyses assume that the location and number of nonrecombining strata in their lineage of interest (lineage 1; see Menkis et al. 2009) are the same as those reported for lineage 6 (Menkis et al. 2008), despite the previous evidence suggesting that these regions may have evolved independently (Menkis et al. 2008, 2009, 2010).
Several strong eQTLs (CDK5RAP2, NBPFs) coincide with regions of reported human lineage selection.
But last year two novel RIPK3 substrates were reported: mixed lineage kinase domain like (MLKL) and phosphoglycerate mutase 5 (PGAM5).
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