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The majority of cases reported MedDRA PTs indicative of motor disturbances with decreased mobility of the injected limb and muscular weakness: most cases reported injection site pain that prevented movement of the injected limb.
Leinisch-Dahlke et al. [13] injected 15 tension headache patients, with prilocaine 1% and dexamethasone, and reported injection site pain in 3 and bradycardia in 1 patient during neck palpation.
None of our patients reported injection site pain.
They reported injection at 100 bar corresponding to around 310 °C.
And the reported injection of seawater, he said, required a breach in the containment vessel, and meant serious long-term releases of radiation.
Sixty-five percent of those admitted for METH/amphetamine abuse reported smoking as the route of administration, eighteen percent reported injection, and 11 percent reported inhalation, [2].
Similar(26)
In a survey of 501 patients with diabetes who used a syringe or pen device to deliver insulin, almost half reported injection-related bruising, and 37% reported injection-related pain.
All of the reported injection-site reactions were mild; none were reported as SAEs or led to discontinuation of the trial product.
Few subjects reported injection-site reactions with IDeg [4.4% (10/226) of participants], and the rate was 15 events per 100 PYE.
The most frequently reported injection-site reactions after APF530 SC administration were induration (55% of subjects), nodules (52%), and hematoma (43%), all of which resolved over time.
Both of these studies reported injection-related reactions, including treatment-site erythema, hyperpigmentation at the treatment site, and pain from the injection itself of about 13%.
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