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Interestingly, in LASP-1 knock out mouse embryo fibroblasts, reported elaboration of several chemokines including CXCL1 might also occur in LASP-KD5 cells [47].
This study is the first reported elaboration of small-molecular-weight fragments against this challenging target.
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Herein we report elaboration of SAR around this hit as well as the syntheses and evaluation of a hundred oxazoline- and oxazole-containing compounds derived from an efficient three step process: 1) formation of β-hydroxy amides with serine or threonine; 2) cyclization to afford oxazolines; and 3) dehydration to give the corresponding oxazoles.
We report the elaboration of new l-Proline functionalized superparamagnetic iron oxide nanoparticles that can act as a new enantioselective organocatalyst.
In this work we report the elaboration of a family of metamagnetic shape memory alloys with composition Mn49Ni42-x FexSn9 (x = 0, 2, 3, 4, 5 and 6 at.%) and the systematic study of their structure, martensitic transformation (MT) behavior and functional characteristics as a function of the Fe doping and magnetic field, up to 12 T.
Readers are referred to the CONSORT PRO Extension for further information on the rationale for each item, examples of reporting and elaboration of the existing CONSORT 2010 statement in relation to PROs [ 11].
In relation to the cognitive dimension, part-time, online students reported more interaction and elaboration in their tutorless group meetings compared to the face-to-face group.
This work reports the successful elaboration of egg white protein/montmorillonite clay nanobiocomposites obtained by thermomechanical processing.
Within the framework of orthosteric G protein coupled receptor (GPCR) polypharmacology herein we report the systematic elaboration and thorough evaluation of a data matrix generated by sampling the chemical space around a common 5,6-fused bicyclic heteroaromatic template applying characteristic pharmacophore elements of central nervous system (CNS) relevant aminergic GPCR ligands.
Among them were M. Slavin & Sons, the fish wholesaler, and an oysterman, Michael Murray, who, it was reported in 1873 without further elaboration, entered his residence eating a piece of pineapple and "when he reached his room he fell dead".
The backfire effect reported by Retailer A (2015) also requires elaboration.
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