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In the potential regime 0 0.4 VAg/AgCl a hitherto not reported defective c(2 × 2) structure was observed.
Several studies of M. ulcerans infected patients have reported defective IFN-γ responses to M. ulcerans antigens [27], [28], [29], [30], [31], [32] as well as to other non-mycobacterial pathogens [33].
Since root meristem function depends on controlled auxin distribution and auxin-mediated gene expression [49], [50], these observations suggest that the mis-direction and hence mis-localization of auxin at the root apex of sterol mutants can account for their previously reported defective root meristem function [21], [26], [31], [33].
Previous studies reported defective paired-pulse R2 inhibition in BEB patients [19], [20] indicating enhanced excitability of brainstem interneuronal pathways [21] We reasoned that the relative loss of paired-pulse inhibition may correlate with abnormal plasticity responses to HFS conditioning in BEB patients.
We previously reported defective branching patterns of reeler PC (Kim et al. 2011).
When these medicines were classified by therapeutic class, those most frequently reported defective were antihypertensives (27/280), antineoplastic agents (21/280) and antibacterials (19/280).
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As for regulatory responsibilities, manufacturers are required to report defective products to the safety administration.
At the urging of industry groups, the White House has objected to a provision that would reward industry whistle-blowers for reporting defective products and another that would give state prosecutors the authority to enforce federal safety laws.
The rate of reporting defective medicines has increased each year over the past 6 years (figure 2).
Here, we report defective thymic negative selection in CBAP-deficient mice via impairment of the assembly of the LAT signalosome and disruption of TCR signaling.
It was reported that defective activity of this complex causes repair defect in patients with xeroderma pigmentosum (XP), an autosomal recessive disorder characterized by photosensitivity and early onset of carcinomas [15,36].
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