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Previous studies on hepcidin regulation have reported a decrease of hepcidin expression in response to hypoxia and anemia [17].
Fabry et al. [32] have previously reported a decrease of calcification as a function of increasing pCO2 but the seawater carbonate chemistry was not reported, preventing a comparison with the present study.
Lowenstein [ 7] reported a decrease of 10° in kyphosis.
19% at baseline and 16% at follow-up reported a decrease of blood pressure.
A Danish study reported a decrease of mean mortality from four to three annual deaths [ 16].
Another study using a checkerboard pattern stimulus of higher luminance reported a decrease of 14.5 % [ 6].
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Experimental evidence supports this hypothesis, reporting a decrease of the catabolic and inflammatory molecules predominantly in cartilage.
Muilenberg et al. report a decrease of the concentration of airborne particles around the front seats when using an AC system [ 15].
Additionally, neoadjuvant trials report a decrease of the rate of metastastic lymph nodes (30 48%)[ 20, 21] compared to initial surgery (60 80%) [ 2, 22- 26].
Namely, much time has passed since CREB was initially associated with AD in seminal studies reporting a decrease of CREB phosphorylation in AD (Yamamoto-Sasaki et al., 1999).
- (Fig. 7) This is agreement with the literature reporting a decrease of BMD by ~3% over six months in patients treated with 1,25(OH D or analogs.
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