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We also report replicated significant association with intron 1 TACR1 mutations in BPAD in the BPALC subgroup and ADS cases in comparison with a screened population of controls.
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The authors' report replicates those research findings but also highlights the complexity of unraveling association from causation and the importance of using the correct methodology when analyzing such data.
Recently reported replicated GWA observations identify a number of genes based on comparisons between controls and European-American and African-American polysubstance abusers.
But soon there were reports of doctored images and plagiarism, and to date, no one has reported replicating the first step in creating STAP cells.
For the PedsQL Cancer Module, exploratory factor analysis identified 8 factors for child self-reports, replicating those of the original theoretical dimensions.
Since the original report of a GxE interaction, hundreds of studies have investigated the combined impact of 5-HTTLPR variation and stress on risk for depression, some of which reported replicating the original findings, while some did not.
To further minimize the impact of sample heterogeneity and the analytical error of metal/Ca ratios, we report replicate measurements of metal/Ca ratios on re-picked G. ruber shells (Table 2).
For the remainder of this report, replicates for each regulatory protein or histone modification were pooled prior to peak calling and the resulting occupancy/enrichment profiles were normalized to 10 million reads.
Prior to the pooled analyses, individual published results – using the same dataset, analytical procedures and adjusting variables as in the original study reports – were replicated and confirmed for all studies on receipt of their data (results not shown).
Most recently, the events of Abbaseyya 2, recounted in the report, were replicated last Sunday at the cathedral – also in Abbaseyya.
In conclusion, we report 26 replicated variance eQTL and 57 replicated cis epistatic interactions, which explain up to 16% of the variance of our phenotypes.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com