To our knowledge, this is the first report of stage-specific expression for a TFIIB-type protein in eukaryotes.
In December 2001, however, the National Confidential Enquiry on Perioperative Deaths (NCEPOD) reported wide variation in hospital caseloads and experience, inadequate staging by clinicians, insufficient reporting of stage by pathologists and poor compliance with treatment guidelines for cancer patients operated as recently as 1999 2000 (NCEPOD, 2001).
Several studies [ 70- 74] report distributions of stage of cancer at diagnosis for African-American women receiving mammograms [Additional File 1: Appendix Table 2].
Presentation of results from use of the CAST instrument, in comparison to WHO criterion, allowed a more detailed reporting of stages of dental caries, which will be useful for oral health planners.
Our data sets for stage-specific transcripts corroborate numerous reports of stage-specific expression of individual genes in B. malayi including serpin in Mf (Bm1_28525) [ 19] and chromadorea ALT protein (Bm1_14360) in L3 [ 20].
Disease status was coded, without the knowledge of the mutational profile, after retrospective review of physician notes and reports of staging radiographs, including tumour measurements; efficacy was assessed on an intent-to-treat basis.
The RCR guidelines on reporting of staging scans make a number of recommendations including description of the primary along with dimensions and image numbers, which nodal chains are enlarged and the dimensions, and a statement about non-malignant changes that may be pertinent.
This study is the first report of the stage dependent cell death only in a population.
Previous studies have relied on self report of pubertal stage, which is a lagging and insensitive measure, that correlates only weakly with measured puberty hormones [ 5].
There were 41 tumor/germline reported markers of stage; 27 (65.9%) were excluded.
In contrast, reported cohorts of stage 4 NB include all age patients, albeit, infant stage 4 NB have a better prognosis than older stage 4 children [ 44].
