Rhianna, a video game writer, replied to a fan's query on Twitter, explaining that she will be involved with "spin-offs, adaptations and tie-ins but that's it".
Adam and Jamie are asking that ideas are submitted either by replying to the video above or posting it in the MythBusters forum.
After all, YouTube had distanced itself from the concept of fans' replying to creators via video when it turned off video responses back in 2013.
You will reply to their glowing morning selfie with a sweat emoji, they will reply to your meme with a "lmao same", you will reply to their video of them walking their labradoodle in Victoria Park with heart eyes, and on it goes.
A 50-year-old former Republican from the Midwest replied to the video on Facebook, calling it "Orwellian nonsense designed to make you cheer and fist pump for your 'freedom' like dogs drooling when the bell gets rung".
"See, I'm a simpleton; I've always had this view that we pay taxes, and the city should do those things," Mr. Jobs replied, according to a video of the meeting.
"There is a war between bin Laden and the whole world," Ahmad Maher, Egypt's foreign minister, replied to the video appeal.
Ms Gutierrez then replied to Brown's video insult in her own video message.
In addition to sharing videos and chatting, YouTube users can also reply to videos they receive with other videos, or even a heart.
Each video you upload can be rated, replied to (video or text), embedded, and accompanied by a set of Flickr photos placed below the recording.
