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Among these, the non-random deposition of histone variants into chromatin that occurs independently of DNA replication, substantially contributes to gene regulation and architectural changes in chromosomes [ 12].
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Furthermore, the production of virus particles and virus replication is substantially inhibited in cells transfected with the suicide vectors pLtBid INS 2R/-CD4.
The absence of detection in about one-quarter of patients on ART in contrast to the Recent SRCV cohort suggests that residual replication is substantially halted with ART.
Nonetheless, incentive schemes [26] or the proposed active distortion-based replication strategy can substantially enhance performance when free-riders are present in video sessions.
MNV-RNA in the supernatant was detected during in vitro replication, which increased substantially from 5 to 30 h post-infection (hpi) and reached more than 1.0 × 1010 copies/mL at 96 hpi.
Previous studies of HCV replicons in which translation was placed under the control of poliovirus IRES, with various lengths of 5'-terminal HCV sequences were retained upstream, indicated that the 5'NTR domain III in HCV contains important replication signals that substantially enhance RNA replication [25], [26].
Taken together, these results illustrate how the benefits of psbA to cyanophage genome replication may vary substantially among infections that occur at different times over the diel cycle, or for cells that are subject to different conditions of irradiance due to mixing [18].
Treatment with antiretroviral therapy does not only suppress virus replication but also substantially reduces HIV-associated general immune activation [ 16- 21].
For practical purposes we generated 1000 data sets for each combination since a larger number of replications would have substantially increased processing time.
However, mitochondrial transcription and replication factors were not substantially affected.
However, between 96 and 110 or 158 h post-infection, total HIV-1 DNA production increased substantially, with replication of 84% of PULSE viruses detected (Figure 3).
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