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To improve simulation performance, an un-identical federate replication structure is proposed in this article.
The replication structure is implemented in a transparent manner without increasing federation scale.
Correctness of the replication structure is proved in theory and verified by experiments.
The experimental results have also shown that the un-identical federate replication structure achieves significant performance enhancement with good scalability and marginal overhead.
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In somatic cells, genetic recombination is one mechanism used for the repair of DNA double-strand breaks and improper replication structures.
Next we analyzed protein dynamics in the replication structures.
During bacteriophage replication, structures form that contain both nucleotide synthesizing enzymes and replication enzymes.
We propose that WRN functions to repair abnormal replication structures caused by the acceleration of DNA replication by c-Myc.
Completion of S phase requires the processing of numerous replication structures including those formed by converging replication forks and replication fork barriers [9], [10], [11], [12].
The recruitment of WRN at sites of DNA replication indicated that WRN might be required to resolve abnormal replication structures during c-Myc-driven S-phase.
Although the assembly steps of some DNA viruses are relatively well known, the intranuclear dynamics of replication structures are poorly understood.
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