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Replication slippage occurs when the replicating strand and the template strand disassociate and then realign out of register, forming a loop in one of the strands.
Replication slippage would result in length variation among the ensemble repeats within a gene, as has been observed in MaSp1, MaSp2, and Flag [26], [41], [49].
Emergence of AFGPs could have proceeded in a step-wise manner that began with accidental replication slippage in an intron of the ancestral trypsinogen gene [12].
replication slippage or unequal crossing over.
Another is intra-chromosomal replication slippage in trans [ 56].
Replication slippage was considered the most likely mutational process.
In general, RBMs include replication slippage (RS; [ 139]), serial replication slippage (SRS; [ 140]), fork stalling and template switching (FoSTeS; [ 141]) and microhomology-mediated break-induced replication (MMBIR; [ 142]).
It is likely that these minicircles were formed by replication slippage.
Replication slippage is a mutational process that expands or contracts microsatellite sequences [ 9].
Indels are mainly caused by replication slippage, which tend to occur in simple tandem repeats.
These repetitive codon tracts are primarily introduced by either replication slippage [ 6] or recombination [ 7].
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