Exact(1)
The reason for the maintenance of the three polymerase polypeptides may be chance or it is quite likely that the three PB1, PB2 and PA polypeptides act most efficiently as a set and so there may be pressure to maintain a gene constellation for optimal replication proficiency.
Similar(59)
We recommend using the 1.5-AUC metric, which incorporates a measure of diagnostic accuracy and proficiency in replication of results with the MTRC, as a first tier test for process improvement.
Therefore, in tissues where the requirements for protection from DNA replication errors are inherently higher, the relative abundance of isoforms with different MMR proficiency may be critical in determining the time and the frequency of cancer pathogenesis.
In previous experiments using pIREShyg2-EGFP- CA 13, the EGFP-positive population consisted of two distinct fractions, M1 and M2, which represent intermediate (correlating with replication errors) and permanent mutant cells (representing the combined effect of replication errors and MMR proficiency) (21).
To assess checkpoint proficiency, we monitored the ability of cells to arrest in mitosis and to prevent re-replication, as well as lack of rebudding.
With proficiency comes progress.
The replication is meticulous.
Many have limited English proficiency.
(Yes, a medal for "proficiency").
Most students had basic proficiency.
I do it with proficiency".
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