Sentence examples for replication population from inspiring English sources

We also replicated another 17 of 21 CpGs, representing 3 additional gene regions, that had achieved genome-wide significance in the previous study but were not replicated in their small replication population using a Bonferroni correction for multiple tests (Joubert et al. 2012).

rs1978423 was not associated with log relative telomere length in either replication population (P≥0.12).

Furthermore, a larger percentage of the replication population had T1DM and the patients with T2DM were significantly younger.

As expected, the "conventional" model, lacking genetic factors, was not significantly associated with nephropathy in the replication population.

The Caucasian replication population includes asthmatic children from the GCC compared to non-asthmatic adults with no family history of asthma from the Cincinnati Control Cohort (CCC).

However, this SNP was not associated with log relative telomere length in the NHS replication population (joint P = 1.4×10−4).

In three black replication populations, which had different linkage disequilibrium patterns than the other populations, original findings were not replicated.

Combined p values for 18,891 white and Hispanic individuals (4,342 cases) in our replication populations were 4.1 × 10−04 for rs1588265 and 9.2 × 10−04 for rs1544791.

In seven white and Hispanic replication populations, two PDE4D SNPs had significant results with p values less than 0.05, and five had results in the same direction as the original population but had p values greater than 0.05.

For both the original and replication populations, nephropathy was defined as the presence of microalbinuria (0.03-0.3 g/gr creatinine), proteinuria (>0.3 g/gr creatinine) or dialysis in the absence of any other unrelated renal disease.

Due to the biological significance of the locus, the authors examined and confirmed associations between rs16847897 and a second SNP at the locus, rs12696304, with telomere length in 3 replication populations.