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One explanation would be that the lytic replication of the viruses may lead to the eventual death of the host cells.
Furthermore, A549 human lung carcinoma cells were infected with human and avian viruses (10 MOI) and treated or not with DPI for 8 h; the haemagglutination assay demonstrated that DPI inhibited replication of the viruses, by about 60% (Fig. S1B>).
The TCID50 assay showed that both the inhibitors strongly reduced the replication of the viruses up to 48 h after the viral challenge (P < 0.001; P < 0.01) (Fig. 5E and F).
Instead, the intracellular diversity arises from the error-prone replication of the viruses themselves, even if the infection in any individual cell is initiated by a single viral genome.
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Additionally, advances in viral based therapy have led to the use of condition replicative adenovirus controlling the replication of the virus mainly through transcription regulation by using tumor specific radioinducible promoters [23, 24].
A prevailing opinion is that replication of the virus must be suppressed as much as possible.
Cocaine greatly enhanced replication of the virus and increased the number of human cells it infected and killed.
They are stained green with antibodies to a nonstructural Zika virus protein, indicating active replication of the virus.
After 2 days at 75 °C, the replication of the virus was monitored by TEM observation of the culture supernatant.
Anti-H.I.V. drugs suppress replication of the virus, which should give the functioning parts of the immune system a chance to eliminate remaining virus.
To stop the replication of the virus, we developed highly potent tetrapeptidic HTLV-I protease inhibitors.
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