Sentence examples for replication of the genome from inspiring English sources
Precise temporal and spatial control of the initiation events is critical for optimal replication of the genome and maintenance of genomic stability (Casper et al., 2008; Foiani et al., 1997; Lemoine et al., 2008).
During replication of the genome, the replicative DNA polymerase Pol III needs to associate tightly with the clamp in order to synthesize very long stretches of DNA.
Thus, the efficient replication of the genome, which depends on a precise temporal and spatial pattern of activation of origins of replication, is greatly impaired.
The vRNP serves as a template for transcription and replication of the genome.
The early mRNAs encode proteins required for replication of the genome and transcription of intermediate stage mRNAs.
The ORF is flanked by structured 5' and 3' untranslated regions (UTRs) that are important for both the translation of the polyprotein and the replication of the genome.
An alternative explanation for the absence of DNA reduplication in the presence of a DNA damaging drug could be that the DNA damage inflicted by the cytotoxic chemotherapeutic drugs inhibits DNA synthesis preventing the subsequent full re-replication of the genome.
In this scenario, the origin function of DS may be required only under conditions where initiation fails at other locations in the viral genome, or if replication of the viral genome is not complete.
The gfp is driven by the HCMV ie promoter and thus, its expression is independent of the replication of the viral genome and starts once the viral genome has reached the nucleus.
Replication of the DEB025res genome proved, unlike replication of the WT genome, to be efficient in CypA KD cells, indicating that the drug resistant genome is less dependent on CypA (and thus likely on the cis-trans isomerase activity) for efficient replication.
Lysogeny is a process by which bacteriophage genomes integrate into the genome of the host, and are transmitted to the progeny during replication of the host genome.
