Sentence examples for replication mode from inspiring English sources

Furthermore, chromosome-specific sequences (pericentromeric, unexpressed DNA arrays), which normally display synchrony in replication of homologous counterparts, similar to biallelically expressed genes, change their inherent replication mode and replicate asynchronously in lymphocytes of patients with cancer, including ovarian [ 18], hematological [ 16] and prostate [ 8, 17] malignancies.

Even satellite chromosome-specific sequences (pericentromeric non-coding DNA arrays), which normally display synchrony in replication of homologous counterparts, similar to biallelically expressed genes, change their inherent replication mode and replicate asynchronously in lymphocytes of patients with cancer, including ovarian [ 34], hematological [ 35] and prostate cancers [ 26].

Because 293A cells lack expression of SV40 large T antigen, the plasmid is replicated transiently using an alternative replication mode that initiates randomly throughout the plasmid (Chandok et al. 2011).

According to our results, each of the cancer patients had an allele-specific replication mode for loci that normally replicate in the classical biallelic-mode.

This virus was previously classified in the Baculoviridae family based on similarity with baculovirus in regard to structure and replication mode.

This observation is consistent with previous findings showing that the θ-type replication mode confers higher segregational and structural stability of plasmids in Bacillus compared to the rolling-circle-type replication (Bron and Luxen 1985).

However, a series of recent studies has demonstrated that mammalian mtDNA replicates via two replication modes, neither of which is identical to the strand-displacement model [3 7].

We will also discuss the parallels between T4 DNA replication modes and similar events in cellular and eukaryotic organelle DNA replication, and close with some current questions of interest concerning the mechanisms of replication, recombination and repair in phage T4.

Illustrations of the genealogies of different replication modes.

While estimates of mutation rates exist for nearly two dozen viruses, estimates of replication modes exist for only a few (Sanjuan et al., 2010).

However, investigations on mammalian mtDNAs suggest possible alternative L-strand syntheses [ 33- 35] or additional replication modes, which might be tissue- or stage-specific [ 36- 40].