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Here we report a replication in which we reconstructed their optical device and measured both perceived size (replicating the main conditions of their experiments) and perceived distance (extending their work).
This is precisely what is expected by the semiconservative mode of replication, in which the original DNA molecules should separate into two template strands containing 15N, and the newly aligned nucleotides should all contain 14N.
The third mechanism, proposed by Max Delbruck, was dispersive replication, in which the parental DNA chains break at intervals and the parental segments combine with new segments to form the daughter strands.
* "bulky adduct formation" (i.e., benzo[a]pyrene diol epoxide-dG adduct, aristolactam I-dA adduct) mismatch of bases, due to errors in DNA replication, in which the wrong DNA base is stitched into place in a newly forming DNA strand, or a DNA base is skipped over or mistakenly inserted.
Additionally, reliability of DNA replication, in which Polδ is involved, affects cancer susceptibility in higher eukaryotes.
One of the major differences between meiosis and mitosis is that the former consists of two consecutive rounds of chromosome separation with only one round of DNA replication, in which chromosome number is reduced to half to produce haploid gametes.
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It could be useful to conduct a quasi-replication in which we match methods from the earlier study.
27 This probability equals the proportion of bootstrap replications in which the ICER is lower than the threshold value.
Specifically, one may estimate the proportion of the 1,000 model replications in which ZOL is cost savings or cost-effective at a given λ (e.g., €30,0000).
We evaluated the models using coverage probabilities (the proportion of replications in which the 95%% credible interval contained the true value) and power (the proportion of replications in which a difference in S and C between the two tests of interest was detected).
Acceptability curves [ 20] can be drawn showing the proportion of model replications in which ZOL is cost-effective versus placebo for increasing levels of λ, providing an indication of the level of uncertainty associated with the results.
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