Sentence examples for replication in response to from inspiring English sources

The yeast Saccharomyces cerevisiae has been invaluable in genetically dissecting the DNA damage checkpoint pathway and recent findings have provided new insights into the architecture of checkpoint protein complexes, in their order of function and in the mechanisms controlling DNA replication in response to DNA damage.

We also engineered the 3' long terminal repeat of SHIV-1157ipd3N4 to contain an extra NF-κB site to accelerate viral replication in response to host cytokines, especially tumor necrosis factor (TNF -α [1].

ppGpp acts as a global regulator in E. coli, causing a redirection of transcription in favour of genes important for starvation survival [6], although it has recently been shown to also control elongation during DNA replication in response to nutritional status [7].

Using the HBV transgenic mouse (lineage 1.3.32) model of chronic infection [13], we previously demonstrated that PPARα did not affect the level of viral biosynthesis under normal physiological conditions but did mediate enhanced viral transcription and replication in response to peroxisome proliferators [14].

However, little is known regarding cellular signaling pathways that regulate mtDNA replication in response to physiological status or developmental cues in a cell.

Thus, delaying replication in response to osmostress must be important both to provide proper adaptive gene expression and to prevent genomic instability.

These results suggest that, while Swi3 mediates full activation of the replication checkpoint in response to stalled replication forks, Swi3 activates a checkpoint-independent pathway to facilitate recovery of collapsed replication forks and the establishment of sister chromatid cohesion.

The loss of the replication checkpoint kinase MEC1 further relieves the arrest in mad2 mutants, demonstrating the additive nature of the SAC and the replication checkpoint in response to HU-induced replication stalling (Garber and Rine 2002).

Since replication resumption from HU arrest requires Cds1 [13] [19], [19], our data suggest that Swi1 Swi3 complex formation plays a critical role in activation of the replication checkpoint and stabilization of stalled replication forks in response to HU.

As expected, taxol treatment confirmed that circulating hemocytes undergo replication and showed that the rate of replication increases in response to infection (1W ANOVA P <0.0001; Figure  7A-C).

The Cds1-dependent replication checkpoint is required for the resumption of stalled replication forks in response to HU [9], [13], [19].