Exact(44)
We report that all mutants have retained their replication competence and that they all, like the SL3-3 wild type (wt), induce T-cell lymphomas when injected into newborn mice of the SWR strain.
The sequence of events leading to the onset of DNA replication is conventionally divided in two interdependent processes: licensing a process during which replication origins acquire replication competence but are kept inactive— and firing a process during which licensed origins are activated but not re-licensed.
We also generated a virus mutant with reintroduced genes restoring virus replication competence (Table 1).
Restoration of replication competence induced activation of pathways involving antigen processing and presentation.
Restoration of replication competence activated pathways involved in processing and presentation of HIV and poxvirus antigens to T cells.
The above-described results focused on pathways expected to be targeted by the B19R deletion and restoration of replication competence.
Similar(16)
The phosphorylation of histone H1 and chromatin decondensation in mid to late G1 and S phases have been suggested to be a prerequisite for DNA-replication competence [ 12, 16, 19, 20].
At present, HBV DNA transfection provides a reliable method to address replication-competence and physical formation of complete virus particles.
These genes are predicted to be involved in core biological functions, such as metabolism, replication, transcription, natural competence, antibiotic resistance, cytoskeleton, and others.
Although all species have the capacity to support high levels of replication of WNV, vector competence differs among and within species [ 12- 14].
Given the tendency to lose competence for prion replication upon repeated passaging [30], inocula were never administered to N2a-PK1 cells that had been subjected to more than 5 passages.
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