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Both the data and the procedure used to compute the conditional rate of replication closely follow the ones used by Schork et al. [ 7].
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Interestingly, Mamu-B*08-associated control of SIVmac239 replication may closely parallel HLA-B27-associated control of HIV replication.
C. crescentus is also unusual in that its DNA replication is closely coordinated with cell division, resulting in the production of a single copy of the bacterial chromosome per division cycle.
The genes for DNA packaging, and in particular nucleases, appear to be of bacterial or bacteriophage origin, as reported by Boyer et al. [36]; while the genes potentially involved in DNA synthesis and replication are most closely related to homologues in endosymbionts (Figure 6; Figure S10 and S11; Table S4).
In particular, the information-processing systems (replication, transcription, translation) closely resemble their eukaryotic counterparts [ 19].
Although this research requires replication, these findings closely parallel earlier work using subjective measures of stress response.
The comparative genomic analysis of replication origins from closely related species can be used to reveal the evolutionary mechanisms that account for the development of multiple origin systems.
Again, Culverhouse et al. have emphasized the importance of matching features of a replication analysis as closely as possible to features of the original published study.
Thus, a comparison of the replication origins from closely related haloarchaeal species should reveal the evolutionary processes responsible for the development of multiple origins in haloarchaea.
Culverhouse et al. carefully and rightly emphasize the importance of matching the design features of a replication analysis as closely as possible to design features of the original publication.
Further, our simulation of Bu-1a loss as a replication-dependent phenomenon closely matches our experimental observations (Supplementary Fig S7).
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