Sentence examples for replication check from inspiring English sources

Nevertheless, given the fact that many independent mutations in different human ORC subunits, where some have been shown to affect replication functions directly, and hypomorphic mutations in the ATR replication check point protein lead to primordial dwarfism, it is hard to escape the inference that loss of ORC replication licensing functions are indeed epistatic to the MGS phenotype.

Technology-based assessments also provide new opportunities for data collection and data saving by using data more efficiently for future analysis, such as meta-analysis that includes replication checks (see Kaufmann et al. 2016).

In agreement with previous studies, we found that the replication check-point regulates telomere replication timing in fission yeast as in budding yeast.

The experiments had an augmented design in Senegal (6 blocks × 6 dates as subplots and 209 acc. as sub-subplot) with 4 replicated check varieties; and a complete block design with 3 replications at 2 sites × 2 years in Madagascar.

Thus, KSHV has devised multiple mechanisms to stringently control RTA expression and activity, thereby keeping lytic replication in check.

This interpretation would suggest that the IMD pathway plays a role in keeping DENV replication in check in a normal infection scenario.

These data are all consistent with the interpretation that loss of jnk2 expression is associated with replication stress check point activation through ATR/Chk1 and p21Waf1 in a p53 independent fashion.

Furthermore, because IRF-3/7 play an indispensible role for the induction of the optimal expression of type I IFNs, their delayed activation, relative to NFκB and AP-1, would likely postpone the onset of type I IFN-mediated innate antiviral responses, thereby greatly compromising the ability of the infected host to keep early viral replication in check.

Furthermore, the heightened susceptibility of UNC93b1-mutant mice to NSV infection is likely explained by a mechanism other than a defect in endosomal TLR signalling, in large part because redundant pathways driving type-I IFN production keep early CNS virus replication in check.

To understand how Pn impacts mtDNA replication, we checked the levels of several key factors of mtDNA replication machinery, including Tamas, TFAM, and Twinkle [ 3].

We conducted a simulation study with 2000 replications to check the method for computing the net benefit for survival time data in the absence of competing risks.