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The results of this study contribute to the understanding of the replication behaviour in cell cultures of several strains of BoHV, which is critical for the rational design of in vitro experiments and vaccine production.
Intracellular replication behaviour of the mutants and the wildtype was quantified by plating dilutions of the lysed cells on BHI agar plates that were incubated at 37°C and 43°C, respectively, for one day.
Moreover, point mutations in the URR in variants of the same PV type lead to changes in the replication behaviour and in the transforming capacity of the viruses [ 19, 20].
Epigenetic mechanisms exist as an interplay between DNA methylation, RNA-mediated chromatin modifications, histone modifications and histone variants, but likely also less well-studied mechanisms, such as the organization of nuclear structure including chromosome replication behaviour (Jablonka and Raz, 2009; Margueron and Reinberg, 2010).
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CEN15-replication behaviour, in normal situations as well as in reaction to cancer status and to the methylation blocking agent, completely mimics a biallelically expressed locus.
This paper focuses on exploring a new method of real-time replication of the dynamic behaviour of prime movers that drive rotating generators involved in energy conversion chains.
Reducing kin competition can be viewed as a cooperative behaviour and replication within a host allows successful resource exploitation (often through the production of shared public goods).
Our model of the initiation of DNA replication only displays oscillatory behaviour when forced with periodic signals from the cell cycle.
Model validity was based on replication of stock reference behaviours with sensitivity evaluated using parameter perturbation and Monte Carlo simulation within a fractional factorial sampling design.
In the late 1960s, prompted by the media's graphic coverage of the assassination of U.S. Sen. Robert F. Kennedy together with increased reports of children incurring serious injuries during attempted replications of dangerous behaviours depicted in television advertisements, the potential effects of television violence on children became a growing public concern.
This resulted in good accordance between the behaviour of the replication initiation network in our model in the combined model.
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