Linkage analysis, peak prioritization, and peak replication assessment were repeated with this second set of camptothecins.
In Table 1, we summarise the relationship between levels of replication, assessment of validity, and establishment of scientific generality.> Replications, regardless of level, should all be welcome.
Similar to the photographic assessment, examiners' first records were used to test the inter-examiner reliability in replication assessment and then disagreements were resolved by discussion.
TP53 (a tumor suppressor gene assigned to chromosome 17), AML1 (a gene assigned to chromosome 21 and involved in the leukaemia-abundant 8 21 translocation) and the pericentomeric satellite sequence of chromosome 17 (CEN17) were used for replication timing assessments.
Our objective was to catalogue scientific decisions underpinning study execution that should be reported to facilitate replication and enable assessment of validity of studies conducted in large healthcare databases.
Replication of TA217 assessment report analysis, presented as WMDs.
Replication of TA217 assessment report analysis, presented as SMDs for comparison.
Independent replication of exposure assessment results has not been possible, making further investigation necessary.
As postnatal stress was not the prime focus of this paper, this could be a chance finding and requires further replication and detailed assessment to ascertain whether this is robust.
Until a solution is found, researchers have no better choice than to increase demands on the threshold for significance and on independent replication for the assessment of interaction findings.
