Sentence examples for replication and spreading from inspiring English sources

Although vaccination may prevent lymphomas formation, it is not known whether it controls viral replication and spreading in the environment.

Depletion of neutrophils in animals prior to VSV administration eliminated uninfected tumor cell apoptosis and permitted more extensive replication and spreading of the virus throughout the tumor.

Numerous viruses can precisely target the innate immune signaling pathway for productive replication and spreading.

Expression of retroviral proteins, thereby retroviral replication and spreading, rigorously depends on the splicing of the viral genome.

Since stromal cells "cross talk" with malignant cells can define tumor outcome it can be hypothesized that, unless simultaneously targeted, they will severely limit CRAd replication and spreading.

For all replication-competent retroviruses, replication and spreading depend on the production of two major RNA species, a full length mRNA and a single-spliced mRNA.

This organizing principle for RNA virus populations confers tolerance to mutations and facilitates replication and spread within the dynamic host environment.

Since IFNα can act in both autocrine and paracrine manners to limit virus replication and spread [27], it appears that LDV is quite resistant to the antiviral effects of IFNα, even when present at very high systemic levels.

However, recent studies have revealed that, even after anti-HSV-2 therapy, recruited HIV receptor-positive T cells and DCs persist at sites of HSV-2 reaction, thereby possibly contributing to continued HIV replication and spread [21].

These data indicate that PT has an inhibitory effect on the early recruitment to the airways of cells that play a significant role in controlling virus replication and spread [70], [71], [72].

In conclusion, data provided herein demonstrated that an impaired host defense against HSV-1 infection in the susceptible DA strain with delayed infiltration of macrophages as well as early recruitment of NK and T cells to the infection site and reduced activation of Tlr2 and -9 influenced HSV-1 entry, replication and spread to the CNS.