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Second, IN is absolutely required for viral replication and mutations in a number of key residues block the viral replication.
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After the flight, DNA replication and mutation frequencies were measured.
We found that there was almost no effect of microgravity on DNA replication and mutation frequency.
The theory of molecular quasispecies has been applied to replication and mutation on single-peak fitness landscapes.
All known living systems contain linear strings of information based on DNA, a molecule that makes Darwinian evolution possible through replication and mutation.
Replication and mutation on neutral networks are modeled by phenomenological rate equations as well as by a stochastic birth-and-death model.
The high replication and mutation rate of hepatitis C virus (HCV) results in a heterogeneous population of viral sequences in vivo.
The predictions of the phenomenological approach on the single-shape landscape are very well reproduced by replication and mutation kinetics of tRNAphe.
Under suboptimal therapy, the combination of both the high rates of replication and mutation leads to the emergence of drug resistance.
These elements do not contain signatures of previously identified retrotransposons, but seem to have undergone replication and mutation.
That the AT skew of the two genes on the opposite strand is not inverted suggests that replication and mutation are likely to be the major processes driving the extreme GC and AT skew of the G. sulphuraria mitochondrial genome.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com