Sentence examples for replication and damage from inspiring English sources

Defective DNA replication and damage can lead to mutagenesis or chromosome pulverization within the micronuclei.

Two forms of ribonucleotide reductase (RR), consisting of M1 with M2 subunits and M1 with p53R2 subunits, are involved in DNA replication and damage repair, respectively.

DCAF proteins are involved in DNA replication and damage repair, cell cycle and tumour suppression [ 70, 73, 77].

SRS2 encodes a helicase that contributes to DNA double-strand break repair, replication and damage signalling (Marini and Krejci 2010).

DAF-19 is involved in regulation of sensory neuron cilium whereas Crt-1 is involved in regulating DNA replication and damage checkpoint pathways [ 10, 12].

It has been proposed that it is logical to use HRR in long-lived quiescent HSCs in order to guard them against errors occurring during DNA replication and damage associated with oxidative stress.

It is important to understand that, although each of the described lesion types differed in pathological severity, level of host control of bacterial replication, and damaging neutrophilic infiltration, all three lesion types continued to increase in size and degree of inflammation over time.

Growth restriction and apoptosis following inhibition of NEDD8-activating enzyme in solid tumor cell lines occurs because of DNA re-replication and damage, yet it is not known whether this occurs in primary lymphoid tumors.

OBFC2A, upregulated by M1775R, and OBFC2B, upregulated by A1789T and in Mut vsWT, encode single-stranded DNA-binding proteins essential for DNA replication, recombination and damage detection and repair.

WEE1 kinase in higher plants is transcriptionally up-regulated in response to both DNA replication and DNA damage checkpoints and it couples the cell cycle block in response to DNA damage with DNA repair [14] (Fig. S1).

Another commonly seen progeroid syndrome is WS, caused by mutations in WRN gene that encodes a RecQ DNA helicase (Yu et al., 1996) important to DNA replication and DNA damage repair.