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Note that we have not provided a comprehensive analysis of replication above.
In obese individuals, the presence of type 2 diabetes was not associated with a significant increase in ductal replication above that already present in obese non-diabetic controls (0.43 ± 0.06% vs 0.34 ± 0.02%, p = NS).
The error-threshold is the error rate of replication above which the sudden onset of the population delocalization from the fittest genotype occurs despite Darwinian selection; i.e., the break down of evolutionary optimization.
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In another example, for the identification of host regulators for HIV replication mentioned as above, overlaps were very limited among the three studies described (Table 1).
As discussed above, replication bypass of the γ-OH-PdG adduct 2 is nearly error-free in E. coli 65− 67); the level of inhibition of DNA synthesis past the lesion was estimated at ∼27% (65).
LANA-associated TIP60 retained its acetyltransferase activity and showed enhanced stability, which is consistent with Li et al.'s finding that TIP60 in critical for KSHV lytic replication (see above).
Although concurrent disruption of both TrxR1 and GSH in hepatocytes prevents DNA replication (see above), it remained untested whether the disulfide reducing power for RNR needed to be transferred from NADPH to the cytosolic disulfide reductase systems.
In most cases (6/8), these sequences exploit a catalytic strategy based on C's (as the unit of replication described above), and their mutational neighborhood is characterized by a lower degree of neutrality, a higher fraction of helpers and a minimal fraction of parasites.
In this case, a ROC analysis for selection of relevant predictors, using PLS regression coefficients, gave a ROC-AUC value of 0.67 (data not shown), as compared to 0.98, when relevant predictors were grouped into a cluster of X (results were averaged on 100 replications of the above simulation).
First, as we discussed above, no replication can definitely prove an earlier study wrong, but close or rigorous partial replication is often the only effective tool for identifying results that are likely wrong.
Based on the above reliable replication of injection nanomolded textured PC film, we subsequently focus on the utility and potential practical applications as anti-reflection layers.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com