The finite element model is able to replicate the structural behavior displayed by the experiments with good accuracy.
Nanofibrous scaffolds, composed of ultra-fine biodegradable polymer fibers, replicate the structural and mechanical anisotropy of native fibrous tissues and serve as a 3D micro-pattern for directing cell orientation and ordered matrix formation.
In this review, we will focus on nanoengineered strategies used to replicate the structural and functional aspects of native biological tissues for engineering bone-cartilage, bone-ligament, and bone-tendon interfaces.
A strategy for corneal tissue engineering was pursued to replicate the structural hierarchy of human corneal stroma within thin stacks of lamellae-like tissues, in this case constructed from scaffolds constructed with RGD-coupled, patterned, porous, mechanically robust and transparent silk films.
Numerical models were developed to replicate the structural response of the compressive member tests and subsequently used to generate parametric results, where the member slenderness, size of prestressing cable, applied prestress level, steel grade (S460 or S690), and grout condition (grouted and non-grouted), were varied.
It is perhaps time to replicate the structural features that made the Marshall Plan a successful outcome.
In many respects, the GFAP-IL6 mouse replicates the structural and functional neuropathology of human neurodegenerative diseases including Alzheimer's disease and HIV-associated dementia [ 46].
Another key consideration in the design of the scaffolds is the difficulty in replicating the complex structural composition of hard tissues such as bones, and its structure cannot be reproduced with a single material that provides a limited range of properties.
Transmission electron microscopy demonstrates that a proportion of the gold nanostructures exhibit structural features replicating the pore space of this ∼1.4 nm maximum pore diameter MOF, as well as regions that are larger in size.
