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These Tetrahymena macronuclear minichromosmes (referred to collectively as rDNA) provide a rich source of telomeres (half of the telomeres in the cell) and a well-characterized replication origin, and have been exploited to create autonomously replicating, high copy number transforming plasmids for antisense and over-expression studies (for review and references see [28] [30]).
Third, a research agenda needs to be formulated to address the gaps in the current knowledge base, which should include replicating high quality studies such as the one by Patel and colleagues in India [ 15].
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The 28-year-old's biological passport showed the use of a banned method for replicating high-altitude conditions.
Large genomic laboratories may want to use PRT as an easy method of replicating high-throughput data by an alternative method with accurate quantification of copy number.
Tabata is a workout timing that replicates High Intensity Interval Training - which involves exercising in short but tough bursts - at its best and most intense.
–Fund managers and professional investors try to replicate high level of gains by taking bigger and bigger risks.
Since poly(dimethyl siloxane) (PDMS) is a compatible material in tissue engineering we explore PDMS casting on Ni masters as an alternative way to replicate high aspect ratio micro structures.
Of course, it is also important to note that "me too" studies commonly claim to replicate high impact observations as a way of publishing follow-on observations.
Previously observed associations were also replicated: higher levels in males, a U-shaped relationship with age, higher levels in current versus never smokers, and higher levels in those who grow their own vegetables (Steenland et al. 2009).
In a previous X-ray crystal structure of a replicating, high-fidelity DNAP, a bend in the DNA primer strand was noted that seems to represent this same 2′-endo to 3′-endo conformational shift in attacking sugar pucker (i site).
In addition, many are capable of rapidly replicating to high numbers at the expense of their host cell.
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