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Using the combined wiki and BIR-TAB metadata approach, we collected unambiguous metadata for 1112 released experiments and connected biological samples to their resulting data and annotations from more than 2700 biological replicates to date.
With a total of 993 million 50 bp reads, corresponding to an entire ABI SOLiD-3+ flowcell per measurement sample, this constitutes one of the largest RNA-Seq datasets featuring technical replicates to date.
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The study, carried out by the International Data Corporation IDCC) and sponsored by big data specialists EMC, is the sixth annual audit of global data inventories, and includes all such material gathered, created and replicated to date.
Although there are hundreds of cloned horses and other animals, Tomatillo is only the second eventing horse to be cloned from a British original; and Tamarillo is arguably the most storied horse of any kind to be replicated to date.
However, only a few genetic associations have been clearly identified and replicated to date, leaving some impetus to search for new candidate genes.
It was reported in 2002 that ARP2/3 activity is essential for platelet filopodia formation [ 126], but this has not been replicated to date.
To construct such a system, Ghadiri first needed more kinds of replicating proteins; to date, his laboratory has identified about eight of them.
An October 2009 paper in Science found XMRV in the blood of two-thirds of the CFS patients examined, but more than a dozen labs have failed to replicate it to date.
The pipeline handles all steps of the process including data download, microarray preprocessing, merging of duplicate probe sets and sample technical replicates, up-to-date probe-set to gene mapping and building of the R/Bioconductor objects and package.
Scientists around the world have tried to replicate the technique, but to date no one has publicly said they've succeeded.
These experiments will be replicated in Protocol 2. To date, conflicting reports of Ras-associated senescence have been reported.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com