In particular, the human immunodeficiency virus type 1 (HIV-1), which replicates using an error-prone reverse transcriptase, has been shown to escape the silencing effects of shRNAs.
Although HBV replicates using an error-prone reverse transcriptase, its small, economically arranged genome limits sequence plasticity, making HBV a good target for RNAi-based therapeutic approaches, which rely on nucleic acid hybridization.
The nine re-extracted individuals corresponding to our replicates gave an error rate of 4.65% (equal to 123 errors divided by nine pairs of replicates and 294 loci) according to Bonin et al.[ 56].
Under these conditions, ML infers the correct tree from all replicates, for an error rate of zero.
To minimize the number of false-positive signals, hybridization data were stringently filtered to obtain genes with at least six statistically significant values out of the eight technical replicates, applying an error probability of less than 5% for the t-test [ 64].
The expected value of K, E K| X) can then be compared against the true value of the number of demes, K T =4, across multiple replicates, to get an error measure that is given by E(E(K| X)− K T ) (Huelsenbeck and Andolfatto, 2007).
Equally, replicating a study with the same number of patients will replicate the error too: observing the same result across different research groups and epochs offers no reassurance.
Rendered in what its creators called Squigglevision — a pseudo-amateurish cartooning style that uses software to replicate human error — the show looked as if it was hand-drawn by an artist on way too much coffee.
As the experiment includes other wild type samples with true replicates, this is likely an error.
I first read it in Geoffrey Grigson's Faber Book of Love Poems, where line 12 was inadvertently omitted, and I've cheerfully replicated the error several times since.
