Exact(13)
We analyzed only these associations in the replication cohort and confirmed associations that were replicated in the same direction as in the discovery cohort (positive or negative in both data sets) with a p < 0.025 in the replication cohort.
These equations describe substitution rates corresponding to evolutionary time under the conditions that the replication timing program is stable (genomic sequences are always replicated in the same order) and that the variations of Γ as a function of t rep are conserved so that a given sequence is always replicated in the presence of the same proportion of dCTPs and dGTPs in the pool of dNTPs.
This means that a data item should not be replicated in the same data center, but be spread across three different ones.
However, this finding was not replicated in the same sample at an older age, although high-risk offspring still exhibited higher afternoon salivary cortisol over a two-week period compared to controls (Ellenbogen et al. 2010) and there was evidence that morning cortisol predicted the development of major mood episodes (Ellenbogen et al. 2011).
The procedure does not assume low-frequency global effects and is based on the assumption that the global signal (the time course of the average intensity per volume) is replicated in the same pattern throughout the brain, although not necessarily at the same magnitude.
And of course twenty-year habits couldn't be replicated in the same lifetime, like holding each other in the morning and laughing at some silly thing no one else would understand or just breathing in synch.
Similar(47)
"HIV and GBV-C somehow use similar sites and similar mechanisms for replication," Manns speculates--meaning, he adds, that they may not be able to replicate in the same cells simultaneously.
This finding may be relevant for vaccination strategies (39 ), especially when considering the use of OPVs as vectors in genetically recombinant vaccines and their ability to undergo spontaneous genetic recombinations with virus relatives when replicating in the same cells of a host.
Future work will be able to explicitly investigate whether the compensation effects identified here replicate in the same or different cohorts; and investigate whether a single weighted measure of structural disease load across the brain may be more appropriate than the four measures (necessitating correction for multiple comparisons) used here.
Three variants were identified, one of which (+1131C>T, from here on referred to as rs2228595) revealed significant (p = 0.002) evidence for association in a German sample of 265 schizophrenics and 227 controls, a finding that did not replicate in the same study either in a second case-control sample or in a family-based association sample, each if which was also of German origin [ 5].
The caveat though is that 3D graphic designers may add things that, while they look good virtually, can't be replicated in the exact same way.
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Justyna Jupowicz-Kozak
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