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Molecular modelling is used to replicate successfully the glass transition temperatures (measured using thermal analysis) of a range of copolymers.
As Table 3 shows, several of the different lines independently converged upon the same mutations suggesting that these mutations, conferring the ability to withstand extreme temperatures, may: (1) be preferred sites of heat mutagenesis [ 15] while (2) maintain the phage's ability to infect and replicate successfully within its host.
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Can similar measures be replicated successfully on a Europe-wide — indeed worldwide — scale?
The recent success of genetics has identified 50 susceptible genes of T2DM in Caucasians by biology candidate study, linkage study and also genome-wide association study, among which some loci such as KCNJ11, TCF7L2, TCF2 genes have been replicated successfully in our Chinese Han population with the odds ratio ranging from 1.14-1.31 1.14-1.31
Even with this technique, only a few types (mainly HPV 11 and 31) have been replicated successfully in laboratory conditions.
Two SNPs on Chr 15 at the CHRNA 3/5 locus (rs8034191 and rs1051730) reached genome-wide significance and were replicated successfully in the independent study cohorts.
This result replicated successfully the difference between constant-context and random-context conditions in previous studies (Müsseler & Kerzel, 2004; Müsseler et al., 2008).
A total of 18 additional top SNPs (P-value<10−5) from the meta-analysis were tested in the GEM cohort and the ATM GWA cohort, but none could be replicated successfully.
(Oddly, no mention is made of the modern epic that replicated most successfully the historical sweep of the earlier generation of pictures: Warren Beatty's 1981 "Reds").
Not all of our findings were replicated; six sites that were tested did not successfully replicate and three sites could not be tested because the data were unavailable.
All pairings replicated once, mostly successfully, but occasional failures of both replicates denoted by gaps (one or both isolates in each replicate did not grow or became contaminated).
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