Compared to other effect studies and meta-analyses (see NICE, 2009), our study could not replicate reported favourable outcomes for auditory hallucinations and negative symptoms.
The study had a power of 55.1% to replicate reported association with bipolar disorder and of 69.1% with schizophrenia (alpha = 0.05%) [ 14, 16].
Rather than replicate reporting guidelines for study designs, the intent of the GREET is that it should provide detailed information for describing the intervention only and should be used in conjunction with existing reporting guidelines for study design.
We conducted a genome-wide association study in 619 healthy unrelated African Americans in an attempt to replicate reported findings in Europeans and Asians and to identify novel loci influencing total serum bilirubin levels.
However, an inability to replicate reported linkage and association findings suggest that prostate cancer is genetically complex with multiple common low-penetrance genes involved in prostate cancer predisposition [ 7].
In this study, after evaluating 301 published studies that attempted to replicate reported disease-associations for 25 different genes, the authors confirmed the disease-associations for eight of these genes.
Identification at genus level was always correct, although in most cases the three replicates reported different identification at species level.
In addition, we replicated reported association between variants in the semaphorin 3C (SEMA3C) gene and bilirubin levels.
Nominal significance was shown for 12 SNPs from BDNF, DRD1, HTR1E, HTR2A, HTR3B, DAT1/SLC6A3, and TPH2 genes replicating reported associations with ADHD.
This explains the weak agreement of same transcript estimates between pairs of replicates reported for BitSeq in Rossell et al. (2014) and is a reminder that it is very important to check the alignment rates.
