Sentence examples for replicate may be from inspiring English sources
This inability to replicate may be due in part to the under-representation of RP in most cohorts.
One replicate may be excluded; if a replicate is excluded, the mean OD must be recalculated using the 3 acceptable values.
If several trans-eQTL in combination with a cis-eQTL contribute to expression control, it is possible that the eQTL deemed strongest in one replicate may be second strongest in another replicate, and vice versa.
Differences among expression patterns for each biological replicate may be explained by biological variation, the probability of sampling a given LongSAGE tag, and/or imperfections in K-means clustering (e.g, variance may not be a good measure of cluster scatter).
Our results lead to a minimal fourfold increase in the sample size requirement for replication studies, and also imply that many loci that appeared not to have been replicated may be in fact true positives, but failed to replicate because the replication sample sizes, and thus power, were too low.
Lesser numbers of replicates may be allowed in water deeper than 200 meters, at those sites where pollution impacts on the bottom are unlikely in the judgment of the EPA management authority.
Because of inherent noise, many replicates may be needed for statistical significance of small effects.
Furthermore, interpreting Kappa under the premise that it should be 1 for perfect replicates may be naive.
Thus, the number of A samples in some replicates may be very small, leading to an inaccurate classifier.
Technical HTS replicates may be unnecessary, but greater variability will result from library construction from the same source material, distinct purifications of the same source material, and, of course, biological replicates.
Slightly different results could be expected with different source materials, microarray platforms or hybridization conditions and optimization of certain parameters or larger number of replicates may be beneficial for particular systems.
