Only 4 out of 1163 replicates correctly detected association at all five causal variants through the P-value-based meta-analysis, whereas none of the replicates achieved this in the OR-based meta-analysis approaches (Table 2).
The RF model had a classification error rate of 26.67 % (22 correct: 8 incorrect), meaning that it was unlikely to have been achieved by chance (21 of 1,000 bootstrap replicates achieved this error rate or lower; P = 0.021).
This RF model had a classification error rate of 63.3%% (11 correct: 19 incorrect) that could easily have been achieved by chance (968 of 1,000 bootstrap replicates achieved this error rate or lower; P = 0.97).
In practice, this effect is far more relevant than the read depth: 10 million mapped reads using two biological replicates achieves approximately the same power as 2 million total reads across four biological replicates, and the difference cannot be compensated by increasing sequence read depth.
All replicate samples achieved a correlation coefficient of greater than 0.985 (data not shown).
The team hoped to replicate results achieved in Jordan, where one study found that use of LAM promoted good exclusive breastfeeding practices.
Instead, we only need to perform 10 permutations per replicate to achieve the same precision level.
A flight to the Earth-Moon libration point is achieved, replicating the achievement of the ARTEMIS mission.
Minimization of replicates can be achieved by running the replicates, one more at a time, until the confidence intervals for the output variables become acceptable [ 14, 26].
We identified the maximum number of replicates (validity) as 100% minus the minimum percentage (at 5%, 10 %, 20 %, 50 %, 80 %, 90 % and 95 replicates to achieve statistical significance for each predictor.
