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For each compound acting on the remaining 5-HTR subtypes (5-HT1A, 5-HT1D, 5-HT1F, 5-HT2B, 5-HT4F, 5-HT6all5-HT2B, 5-HT2classic4, 5-HT5A, 5-HT6, 5-HT7), all classic bioisosteric replacements implemented in Pipeline Pilot[ 17] (divided into six classes: ring, amide, carbonyl, halogen and hydroxyl substitutions and ring modifications) were applied.
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Initial phases for the FPPS N-BP complexes were calculated by molecular replacement implemented in PHASER [32] using the wtFPPS N-BP in complexesith ZOL (PDB code: 1Zwereas a starting model.
The results of the EnergyPlus™ simulation modeling revealed that reductions of 1.3 1.9% and 2.6 3.8% of the total monthly electricity consumption can be achieved from the 50% cool roof replacement already implemented and a future 100% roof replacement, respectively.
The structures were solved by molecular replacement, as implemented in the program PHASER23.
The structure was solved by the molecular replacement method implemented in Phenix Phaser-MR43, using the model of C1C2 (PDB: 3UG9).
In 2011 a bundled payment pilot program for total hip replacement was implemented by an integrated health care delivery system in conjunction with a commercial health plan subsidiary.
It also needs O(n) time to update the graph any time the graph is changed, i.e. a replacement is implemented.
(In Hallett (1984), it is argued that the system of von Neumann was the first system in which the Axiom of Replacement was implemented correctly (there were technical problems with Fraenkel's formulation), so it may actually be the first implementation of ZFC).
The phase problem was solved using molecular replacement as implemented in MOLREP.
Medical management of acute kidney injury has traditionally consisted of supportive care, with renal replacement therapy implemented for the most severe cases.
All structures were solved by molecular replacement, as implemented in Phaser (McCoy et al., 2007), part of the CCP4 software package (Winn et al., 2011).
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