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Khashan [12] developed FragVLib, a virtual library of fragments which enables finding bioisosteric replacements based on a subgraph matching tool that identifies similar binding pockets according to their 3D structures and chemical composition.
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This study assesses the feasibility of transapical pulmonary valve replacement based on a new valved stent construction concept.
Wear debris related osteolysis is recognised as being the main cause of failure in joint replacements based on UHMWPE inserts.
In this work we present Base of Bioisosterically Exchangeable Replacements (BoBER), a new web server for identification of bioisosteric and scaffold hopping replacements based on our PDB mining approach [14].
The methodology can help pipeline engineers and asset managers in prioritizing pipeline repairs and/or replacements based on their estimated probability of failure.
The evolution of Mt proteins has been studied using different classifications of amino acid replacements based on charge, polarity, and size [17].
To further investigate the functional ramifications of evolutionary change in snake COI, we dissected the details of evolutionary modifications in each channel individually (Figure 3) and inferred the impact of replacements based on existing hypotheses concerning CO function.
In this study, we evaluated the short-term results of computer-navigated knee replacements based on data from the Norwegian Arthroplasty Register.
In some cases, the veterinary officers suggested new villages as replacements based on unavailability of pigs in some of the originally selected villages.
They found no evidence that scheduled replacement, using either of the replacement techniques, at three days or seven days had any advantage over a replacement based on clinical indication.
Select a ballast that has either the exact same part number or is a direct replacement based on type (electronic or electromagnetic technology) input voltage, number and type of lamps, wattage and if desired, sound rating.
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