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We have three observations: (1) for all graph algorithms on all datasets, the batch replacement variants of the two graph databases outperform their original versions.
Hence, they are also known as replacement variants [ 1].
We confirmed all six replacement variants by Sanger sequencing (data not shown).
We verified the replacement variants we identified that were within the genomic interval linked to the phenotype through Sanger sequencing.
The epigenetic functions of these replacement variants are determined by their distinct compositional and structural properties and by different post-translational modifications.
No replacement variants have been identified among H2Bs and all OdH2B genes are intron-less and contain the SL in their 3'UTR (Additional File 1, Table S1).
Similar(43)
RV, replacement variant.
Instead, a 20 kDa band was visible, representing 'protein X', which has been proposed as an H3 replacement variant [ 30].
A common amino acid replacement variant was identified in exon 1 of NDUFC2 (rs8875) in our tested population (Ashkenazi Jews).
The histone H2A family encompasses the greatest number of core histone variants of which the replacement variant H2A.Z is currently one of the most heavily studied.
Variants H1.3 and H1.4 were expressed from orphan genes that contain one intron and a degenerate SL, suggesting replacement variant function.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com