Exact(1)
In addition to a replacement PATH station at the World Trade Center site, which Port Authority officials said yesterday would cost $1.5 billion to $2 billion, the plans released Tuesday portray a new transit center on the east side of Broadway between Fulton and John Streets and an underground concourse connecting the two stations with Battery Park City.
Similar(59)
A permitted replacement along path I can be either effectively neutral or driven by substantial positive selection.
Informally, replacements along path I mark evolvable sites, and replacements, at these sites, along path II tell us how such evolvable sites evolve.
For a preview of what this new Finder might look like, check out advanced 3rd-party Finder replacements like Path Finder.
Once I saw a woman in court and blurted out, "You look like Carly on General Hospital!" I immediately apologized for saying something so stupid when she blurted back, "I love Carly!" My replacement escape paths look bleak right now.
In the case of mammalian or yeast trees, replacements along path I and path II may also occur in the opposite directions, thus constituting a reversal; for example, a site with A in dog and rat and B in human and mouse can emerge due to A→B replacement in the lineage that led to the common ancestor of human, mouse, and rat, followed by B→A replacement in the rat lineage.
The sign of this difference is as expected: because rates of nonsynonymous substitutions are strongly heterogeneous across sites [ 6, 17], a replacement observed along path I must be a good predictor of the probability of a replacement, at the same site, along path II.
If fitness landscapes are different along paths I and II, some replacements permitted along path I are forbidden along path II.
This deficit may be caused by changes in the fitness landscape, leading to a replacement being possible along path I but not along path II.
An amino acid replacement which occurred along path I also occurs along path II with the probability 50 80% of that expected under selective neutrality.
The rate of coincident divergent evolution, such that an amino acid replacement A↔C occurred along path II at an amino acid site where an amino acid replacement A↔B occurred along path I, is always much lower than the rate of parallel nonsynonymous evolution, but still higher than the average rate of all nonsynonymous substitutions (Tables 1, 2, 3).
Write better and faster with AI suggestions while staying true to your unique style.
Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com