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Machiels, B. et al. A gammaherpesvirus provides protection against allergic asthma by inducing the replacement of resident alveolar macrophages with regulatory monocytes.
In summary, normal hepatocyte transplantation is able to delay DENA+RS-induced carcinogenic process and it is also associated with extensive remodeling of the tissue landscape, consisting in the massive replacement of resident senescent hepatocytes with phenotypically normal cells.
For instance, one of the leading hypotheses for the replacement of resident red squirrels by invasive grey squirrels in the UK is the differential susceptibility to a parapoxvirus brought by the invasive greys (Rushton et al. 2000; Tompkins et al. 2002).
The introduction of H58 appears to be associated with clonal replacement of resident non-H58 antibiotic-susceptible strains, resulting in transformation of the Salmonella Typhi epidemiology across Africa and the occurrence of multidrug-resistant outbreaks in regions where the disease was previously underappreciated [ 7].
The extremely high rates of disease among plants that were inoculated with one type of pathogen and then with water as a control (Table 1), particularly for the M. silenes-inflatae treatment, indicates that the super-infection category was most often the replacement of resident infection rather than failure of the first inoculation to colonize the host.
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The evolutionary dynamics of the consumer trait is based on the occurrence of mutant strategies ( <img src="http://journals.plos.org/plosone/article/asset?id=info?doi/10.1371/journal.pone.0006731.e004.PNG" class= inline-graphic"/> ) within the resident population of the consumer species and replacement of the resident strategy (ui) by a mutant strategy as determined by its invasion fitness.
King and Attardi [47] have previously demonstrated that micro-injection of mitochondria into cell lines depleted of their own mitochondrial DNA allowed for the replacement of the resident mtDNA by exogenous mtDNA.
Thereafter, we propose processes that can favour the replacement of the resident by the mutant as observed in data.
However, data clearly suggest that several recurrent epidemics of the same new mutant cluster can follow the replacement of the resident cluster by the new one.
PCR tests of the few recovered transformants showed replacement of the resident intact rdxA gene by the ΔrdxA-cat allele, indicating homologous recombination, not cat insertion into an ectopic site.
The latter was derived from pCM252 [44] by replacement of the resident ScTRP1 gene (ScaI fragment) by ScURA3 which had been isolated from YCplac33 [43] by partial digestion with ScaI.
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